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Deamidation alters interactions of β-crystallins in hetero-oligomers

PURPOSE: Cataracts are a major cause of blindness worldwide. A potential mechanism for loss of visual acuity may be due to light scattering from disruption of normal protein–protein interactions. During aging, the lens accumulates extensively deamidated crystallins. We have previously reported that...

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Bibliografske podrobnosti
Main Authors: Takata, Takumi, Woodbury, Luke G., Lampi, Kirsten J.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633459/
https://ncbi.nlm.nih.gov/pubmed/19190732
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