In vivo PET Imaging of [(11)C]CIMBI-5, a 5-HT(2A)R Agonist Radiotracer in Nonhuman Primates

Purpose: 5-HT(2A)R exists in high and low affinity states. Agonist PET tracers measure binding to the active high affinity site and thus provide a functionally relevant measure of the receptor. Limited in vivo data have been reported so far for a comparison of agonist versus antagonist tracers for 5...

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Detalhes bibliográficos
Publicado no:J Pharm Pharm Sci
Main Authors: Prabhakaran, Jaya, DeLorenzo, Christine, Zanderigo, Francesca, Knudsen, Gitte M., Gillings, Nic, Pratap, Mali, Jorgenson, Matthew J., Daunais, James, Kaplan, Jay R., Parsey, Ramin V., Mann, J. John, Kumar, J.S. Dileep
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453972/
https://ncbi.nlm.nih.gov/pubmed/31356761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18433/jpps30329
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