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Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology

Ependymoma (EPN) is a brain tumor commonly presenting in childhood that remains fatal in most children. Intra-tumoral cellular heterogeneity in bulk-tumor samples significantly confounds our understanding of EPN biology, impeding development of effective therapy. We, therefore, use single-cell RNA s...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Gillen, Austin E., Riemondy, Kent A., Amani, Vladimir, Griesinger, Andrea M., Gilani, Ahmed, Venkataraman, Sujatha, Madhavan, Krishna, Prince, Eric, Sanford, Bridget, Hankinson, Todd C., Handler, Michael H., Vibhakar, Rajeev, Jones, Ken L., Mitra, Siddhartha, Hesselberth, Jay R., Foreman, Nicholas K., Donson, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452755/
https://ncbi.nlm.nih.gov/pubmed/32783945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108023
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