Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology

Ependymoma (EPN) is a brain tumor commonly presenting in childhood that remains fatal in most children. Intra-tumoral cellular heterogeneity in bulk-tumor samples significantly confounds our understanding of EPN biology, impeding development of effective therapy. We, therefore, use single-cell RNA s...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Gillen, Austin E., Riemondy, Kent A., Amani, Vladimir, Griesinger, Andrea M., Gilani, Ahmed, Venkataraman, Sujatha, Madhavan, Krishna, Prince, Eric, Sanford, Bridget, Hankinson, Todd C., Handler, Michael H., Vibhakar, Rajeev, Jones, Ken L., Mitra, Siddhartha, Hesselberth, Jay R., Foreman, Nicholas K., Donson, Andrew M.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452755/
https://ncbi.nlm.nih.gov/pubmed/32783945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108023
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