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DOK7 Gene Therapy Enhances Neuromuscular Junction Innervation and Motor Function in Aged Mice

Muscle denervation at the neuromuscular junction (NMJ), the essential synapse between motor neuron and skeletal muscle, is associated with age-related motor impairment. Therefore, improving muscle innervation at aged NMJs may be an effective therapeutic strategy for treating the impairment. We previ...

詳細記述

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書誌詳細
出版年:iScience
主要な著者: Ueta, Ryo, Sugita, Satoshi, Minegishi, Yoshihiko, Shimotoyodome, Akira, Ota, Noriyasu, Ogiso, Noboru, Eguchi, Takahiro, Yamanashi, Yuji
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452162/
https://ncbi.nlm.nih.gov/pubmed/32758427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101385
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