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In Vivo Estimates of Liver Metabolic Flux Assessed by (13)C-Propionate and (13)C-Lactate Are Impacted by Tracer Recycling and Equilibrium Assumptions
Isotope-based assessment of metabolic flux is achieved through a judicious balance of measurements and assumptions. Recent publications debate the validity of key assumptions used to model stable isotope labeling of liver metabolism in vivo. Here, we examine the controversy surrounding estimates of...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451222/ https://ncbi.nlm.nih.gov/pubmed/32755580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107986 |
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