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An analytic and systematic framework for estimating metabolic flux ratios from (13)C tracer experiments

BACKGROUND: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for estimating the metabolic fluxes from (13)C isotopomer measurement data rely either on manual derivation of analytic equati...

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Autors principals: Rantanen, Ari, Rousu, Juho, Jouhten, Paula, Zamboni, Nicola, Maaheimo, Hannu, Ukkonen, Esko
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430715/
https://ncbi.nlm.nih.gov/pubmed/18534038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-266
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