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Evaluation of (13)C isotopic tracers for metabolic flux analysis in mammalian cells

(13)C metabolic flux analysis (MFA) is the most comprehensive means of characterizing cellular metabolic states. Uniquely labeled isotopic tracers enable more focused analyses to probe specific reactions within the network. As a result, the choice of tracer largely determines the precision with whic...

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Autori principali: Metallo, Christian M., Walther, Jason L., Stephanopoulos, Gregory
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026314/
https://ncbi.nlm.nih.gov/pubmed/19622376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2009.07.010
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