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Evaluation of (13)C isotopic tracers for metabolic flux analysis in mammalian cells

(13)C metabolic flux analysis (MFA) is the most comprehensive means of characterizing cellular metabolic states. Uniquely labeled isotopic tracers enable more focused analyses to probe specific reactions within the network. As a result, the choice of tracer largely determines the precision with whic...

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Bibliographic Details
Main Authors: Metallo, Christian M., Walther, Jason L., Stephanopoulos, Gregory
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026314/
https://ncbi.nlm.nih.gov/pubmed/19622376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2009.07.010
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