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Optimization of (13)C isotopic tracers for metabolic flux analysis in mammalian cells

Mammalian cells consume and metabolize various substrates from their surroundings for energy generation and biomass synthesis. Glucose and glutamine, in particular, are the primary carbon sources for proliferating cancer cells. While this combination of substrates generates static labeling patterns...

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Detalhes bibliográficos
Main Authors: Walther, Jason L., Metallo, Christian M., Zhang, Jie, Stephanopoulos, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586220/
https://ncbi.nlm.nih.gov/pubmed/22198197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2011.12.004
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