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Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines

BACKGROUND: Bupropion (BUP) is widely used as an antidepressant and smoking cessation aid. There are three major pharmacologically active metabolites of BUP, Erythrohydrobupropion (EB), Hydroxybupropion (OHB) and Threohydrobupropion (TB). At present, the mechanisms underlying the overall disposition...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Metab Lett
Main Authors: Han, Lyrialle W., Gao, Chunying, Zhang, Yuchen, Wang, Joanne, Mao, Qingcheng
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451048/
https://ncbi.nlm.nih.gov/pubmed/30488806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872312813666181129101507
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