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Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines
BACKGROUND: Bupropion (BUP) is widely used as an antidepressant and smoking cessation aid. There are three major pharmacologically active metabolites of BUP, Erythrohydrobupropion (EB), Hydroxybupropion (OHB) and Threohydrobupropion (TB). At present, the mechanisms underlying the overall disposition...
Enregistré dans:
| Publié dans: | Drug Metab Lett |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451048/ https://ncbi.nlm.nih.gov/pubmed/30488806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872312813666181129101507 |
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