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Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines

BACKGROUND: Bupropion (BUP) is widely used as an antidepressant and smoking cessation aid. There are three major pharmacologically active metabolites of BUP, Erythrohydrobupropion (EB), Hydroxybupropion (OHB) and Threohydrobupropion (TB). At present, the mechanisms underlying the overall disposition...

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Foilsithe in:Drug Metab Lett
Main Authors: Han, Lyrialle W., Gao, Chunying, Zhang, Yuchen, Wang, Joanne, Mao, Qingcheng
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451048/
https://ncbi.nlm.nih.gov/pubmed/30488806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1872312813666181129101507
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