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An update on expression and function of p-gp/abcb1 and bcrp/abcg2 in the placenta and fetus

INTRODUCTION: P-gp/ABCB1 and BCRP/ABCG2 are highly expressed in the placenta and fetus throughout gestation and can modulate exposure and toxicity of drugs and xenobiotics to the vulnerable fetus during the sensitive times of growth and development. We aim to provide an update on current knowledge o...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Metab Toxicol
Main Authors: Han, Lyrialle W., Gao, Chunying, Mao, Qingcheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290921/
https://ncbi.nlm.nih.gov/pubmed/30010462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2018.1499726
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