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An update on expression and function of p-gp/abcb1 and bcrp/abcg2 in the placenta and fetus

INTRODUCTION: P-gp/ABCB1 and BCRP/ABCG2 are highly expressed in the placenta and fetus throughout gestation and can modulate exposure and toxicity of drugs and xenobiotics to the vulnerable fetus during the sensitive times of growth and development. We aim to provide an update on current knowledge o...

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Pubblicato in:Expert Opin Drug Metab Toxicol
Autori principali: Han, Lyrialle W., Gao, Chunying, Mao, Qingcheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290921/
https://ncbi.nlm.nih.gov/pubmed/30010462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2018.1499726
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