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An update on expression and function of p-gp/abcb1 and bcrp/abcg2 in the placenta and fetus

INTRODUCTION: P-gp/ABCB1 and BCRP/ABCG2 are highly expressed in the placenta and fetus throughout gestation and can modulate exposure and toxicity of drugs and xenobiotics to the vulnerable fetus during the sensitive times of growth and development. We aim to provide an update on current knowledge o...

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Библиографические подробности
Опубликовано в: :Expert Opin Drug Metab Toxicol
Главные авторы: Han, Lyrialle W., Gao, Chunying, Mao, Qingcheng
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290921/
https://ncbi.nlm.nih.gov/pubmed/30010462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2018.1499726
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