Hepatic Transport of 25-Hydroxyvitamin D(3) Conjugates: A Mechanism of 25-Hydroxyvitamin D(3) Delivery to the Intestinal Tract

Vitamin D(3) is an important prohormone critical for maintaining calcium and phosphate homeostasis in the body and regulating drug-metabolizing enzymes and transporters. 25-Hydroxyvitamin D(3) (25OHD(3)), the most abundant circulating metabolite of vitamin D(3), is further transformed to the biologi...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Gao, Chunying, Liao, Michael Z., Han, Lyrialle W., Thummel, Kenneth E., Mao, Qingcheng
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Special Section on Transporters in Drug Disposition and Pharmacokinetic Prediction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896369/
https://ncbi.nlm.nih.gov/pubmed/29467214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.078881
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