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Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy
Cellular recognition of microbial DNA is an evolutionarily conserved mechanism by which the innate immune system detects pathogens. Cyclic GMP-AMP synthase (cGAS) and its downstream effector, stimulator of interferon genes (STING), are involved in mediating fundamental innate antimicrobial immunity...
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| Publicado no: | Mol Cancer |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7450153/ https://ncbi.nlm.nih.gov/pubmed/32854711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01250-1 |
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