Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy

Cellular recognition of microbial DNA is an evolutionarily conserved mechanism by which the innate immune system detects pathogens. Cyclic GMP-AMP synthase (cGAS) and its downstream effector, stimulator of interferon genes (STING), are involved in mediating fundamental innate antimicrobial immunity...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cancer
Autori principali: Zheng, Juyan, Mo, Junluan, Zhu, Tao, Zhuo, Wei, Yi, Yueneng, Hu, Shuo, Yin, Jiye, Zhang, Wei, Zhou, Honghao, Liu, Zhaoqian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450153/
https://ncbi.nlm.nih.gov/pubmed/32854711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01250-1
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