Muscarinic-dependent phosphorylation of the cardiac ryanodine receptor by protein kinase G is mediated by PI3K–AKT–nNOS signaling

Post-translational modifications of proteins involved in calcium handling in myocytes, such as the cardiac ryanodine receptor (RyR2), critically regulate cardiac contractility. Recent studies have suggested that phosphorylation of RyR2 by protein kinase G (PKG) might contribute to the cardioprotecti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Baine, Stephen, Thomas, Justin, Bonilla, Ingrid, Ivanova, Marina, Belevych, Andriy, Li, Jiaoni, Veeraraghavan, Rengasayee, Radwanski, Przemyslaw B., Carnes, Cynthia, Gyorke, Sandor
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2020
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450129/
https://ncbi.nlm.nih.gov/pubmed/32580946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014054
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