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Super-resolution Imaging Using Novel High Fidelity Antibody Reveals Close Association of Neuronal Sodium Channel Na(V)1.6 with Ryanodine Receptors in Cardiac Muscle

The voltage-gated sodium channel Na(V)1.6 has recently been found in cardiac myocytes. Emerging studies indicate a role for Na(V)1.6 in ionic homeostasis as well as arrhythmogenesis. Little is known about the spatial organization of these channels in cardiac muscle, due mainly to the lack of high fi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Microsc Microanal
Hauptverfasser: Struckman, Heather L., Baine, Stephen, Thomas, Justin, Mezache, Louisa, Mykytyn, Kirk, Györke, Sándor, Radwański, Przemysław B., Veeraraghavan, Rengasayee
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061261/
https://ncbi.nlm.nih.gov/pubmed/31931893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1431927619015289
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