HI-511 overcomes melanoma drug resistance via targeting AURKB and BRAF V600E

Rationale: Melanoma is an aggressive tumor of the skin and drug resistance is still a major problem in melanoma therapy. Novel targets and effective agents to overcome drug resistant melanoma are urgently needed in clinical therapy. Methods: Gene Expression Omnibus (GEO) database analysis, pathway e...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Chang, Xiaoyu, Zhang, Tianshun, Wang, Qiushi, Rathore, Moeez Ghani, Reddy, Kanamata, Chen, Hanyong, Shin, Seung Ho, Ma, Wei-ya, Bode, Ann M, Dong, Zigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449901/
https://ncbi.nlm.nih.gov/pubmed/32863956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.44342
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