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Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones
Antibiotic resistance is rising and we urgently need to gain a better quantitative understanding of how antibiotics act, which in turn would also speed up the development of new antibiotics. Here, we describe a computational model (COMBAT-COmputational Model of Bacterial Antibiotic Target-binding) t...
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| Vydáno v: | PLoS Comput Biol |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7449454/ https://ncbi.nlm.nih.gov/pubmed/32797079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008106 |
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