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Using Chemical Reaction Kinetics to Predict Optimal Antibiotic Treatment Strategies

Identifying optimal dosing of antibiotics has proven challenging—some antibiotics are most effective when they are administered periodically at high doses, while others work best when minimizing concentration fluctuations. Mechanistic explanations for why antibiotics differ in their optimal dosing a...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Abel zur Wiesch, Pia, Clarelli, Fabrizio, Cohen, Ted
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5257006/
https://ncbi.nlm.nih.gov/pubmed/28060813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005321
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