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Reaction Kinetic Models of Antibiotic Heteroresistance

Bacterial heteroresistance (i.e., the co-existence of several subpopulations with different antibiotic susceptibilities) can delay the clearance of bacteria even with long antibiotic exposure. Some proposed mechanisms have been successfully described with mathematical models of drug-target binding w...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Martinecz, Antal, Clarelli, Fabrizio, Abel, Sören, Abel zur Wiesch, Pia
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719119/
https://ncbi.nlm.nih.gov/pubmed/31443146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20163965
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