Population Pharmacokinetics and Target Attainment of Cefepime in Critically Ill Patients and Guidance for Initial Dosing

Cefepime is commonly used in the intensive care unit (ICU) to treat bacterial infections. The time during which the free cefepime concentration is above the MIC (fT(>MIC)) should be optimized to increase the efficacy of the regimen. We aim to optimize the exposure of cefepime in ICU patients by u...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Al-Shaer, Mohammad H., Neely, Michael N., Liu, Jiajun, Cherabuddi, Kartikeya, Venugopalan, Veena, Rhodes, Nathaniel J., Klinker, Kenneth, Scheetz, Marc H., Peloquin, Charles A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2020
Aiheet:
Clinical Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449216/
https://ncbi.nlm.nih.gov/pubmed/32601155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00745-20
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