Cefepime Population Pharmacokinetics and Target Attainment in Critically Ill Patients on Continuous Renal Replacement Therapy

Sepsis causes half of acute kidney injuries in the intensive care unit (ICU). ICU patients may need continuous renal replacement therapy (CRRT), which will affect their antimicrobial exposure. We aimed to build a cefepime population pharmacokinetic (PK) model in CRRT ICU patients and perform simulat...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Al-Shaer, Mohammad H., Philpott, Carolyn D., Droege, Christopher A., Courter, Joshua D., Healy, Daniel P., Droege, Molly E., Ernst, Neil E., Mueller, Eric W., Peloquin, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316051/
https://ncbi.nlm.nih.gov/pubmed/33722885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00144-21
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