Population Pharmacokinetics and Target Attainment of Cefepime in Critically Ill Patients and Guidance for Initial Dosing

Cefepime is commonly used in the intensive care unit (ICU) to treat bacterial infections. The time during which the free cefepime concentration is above the MIC (fT(>MIC)) should be optimized to increase the efficacy of the regimen. We aim to optimize the exposure of cefepime in ICU patients by u...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Al-Shaer, Mohammad H., Neely, Michael N., Liu, Jiajun, Cherabuddi, Kartikeya, Venugopalan, Veena, Rhodes, Nathaniel J., Klinker, Kenneth, Scheetz, Marc H., Peloquin, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449216/
https://ncbi.nlm.nih.gov/pubmed/32601155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00745-20
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