Population Pharmacokinetics and Target Attainment of Cefepime in Critically Ill Patients and Guidance for Initial Dosing

Cefepime is commonly used in the intensive care unit (ICU) to treat bacterial infections. The time during which the free cefepime concentration is above the MIC (fT(>MIC)) should be optimized to increase the efficacy of the regimen. We aim to optimize the exposure of cefepime in ICU patients by u...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Al-Shaer, Mohammad H., Neely, Michael N., Liu, Jiajun, Cherabuddi, Kartikeya, Venugopalan, Veena, Rhodes, Nathaniel J., Klinker, Kenneth, Scheetz, Marc H., Peloquin, Charles A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Clinical Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449216/
https://ncbi.nlm.nih.gov/pubmed/32601155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00745-20
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