Caspofungin Weight-Based Dosing Supported by a Population Pharmacokinetic Model in Critically Ill Patients

The objective of this study was to develop a population pharmacokinetic model and to determine a dosing regimen for caspofungin in critically ill patients. Nine blood samples were drawn per dosing occasion. Fifteen patients with (suspected) invasive candidiasis had one dosing occasion and five had t...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Märtson, Anne-Grete, van der Elst, Kim C. M., Veringa, Anette, Zijlstra, Jan G., Beishuizen, Albertus, van der Werf, Tjip S., Kosterink, Jos G. W., Neely, Michael, Alffenaar, Jan-Willem
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449215/
https://ncbi.nlm.nih.gov/pubmed/32660990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00905-20
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