Low Caspofungin Exposure in Patients in Intensive Care Units

In critically ill patients, drug exposure may be influenced by altered drug distribution and clearance. Earlier studies showed that the variability in caspofungin exposure was high in intensive care unit (ICU) patients. The primary objective of this study was to determine if the standard dose of cas...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: van der Elst, Kim C. M., Veringa, Anette, Zijlstra, Jan G., Beishuizen, Albertus, Klont, Rob, Brummelhuis-Visser, Petra, Uges, Donald R. A., Touw, Daan J., Kosterink, Jos G. W., van der Werf, Tjip S., Alffenaar, Jan-Willem C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278683/
https://ncbi.nlm.nih.gov/pubmed/27855112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01582-16
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