Pharmacokinetic Modeling and Optimal Sampling Strategies for Therapeutic Drug Monitoring of Rifampin in Patients with Tuberculosis

Rifampin, together with isoniazid, has been the backbone of the current first-line treatment of tuberculosis (TB). The ratio of the area under the concentration-time curve from 0 to 24 h (AUC(0–24)) to the MIC is the best predictive pharmacokinetic-pharmacodynamic parameter for determinations of eff...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antimicrob Agents Chemother
मुख्य लेखकों: Sturkenboom, Marieke G. G., Mulder, Leonie W., de Jager, Arthur, van Altena, Richard, Aarnoutse, Rob E., de Lange, Wiel C. M., Proost, Johannes H., Kosterink, Jos G. W., van der Werf, Tjip S., Alffenaar, Jan-Willem C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2015
विषय:
Pharmacology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505200/
https://ncbi.nlm.nih.gov/pubmed/26055359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00756-15
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