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The ASC-1 Complex Disassembles Collided Ribosomes

Translating ribosomes that slow excessively incur collisions with trailing ribosomes. Persistent collisions are detected by ZNF598, a ubiquitin ligase that ubiquitinates sites on the ribosomal 40S subunit to initiate pathways of mRNA and protein quality control. The collided ribosome complex must be...

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書目詳細資料
發表在:Mol Cell
Main Authors: Juszkiewicz, Szymon, Speldewinde, Shaun H., Wan, Li, Svejstrup, Jesper Q., Hegde, Ramanujan S.
格式: Artigo
語言:Inglês
出版: Cell Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447978/
https://ncbi.nlm.nih.gov/pubmed/32579943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.06.006
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