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UBE2O is a quality control factor for orphans of multi-protein complexes
Many nascent proteins are assembled into multi-protein complexes of defined stoichiometry. Imbalances in the synthesis of individual subunits result in orphans. How orphans are selectively eliminated to maintain protein homeostasis is poorly understood. Here, we found that the conserved ubiquitin-co...
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| Publicado no: | Science |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5549844/ https://ncbi.nlm.nih.gov/pubmed/28774922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan0178 |
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