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UBE2O is a quality control factor for orphans of multi-protein complexes

Many nascent proteins are assembled into multi-protein complexes of defined stoichiometry. Imbalances in the synthesis of individual subunits result in orphans. How orphans are selectively eliminated to maintain protein homeostasis is poorly understood. Here, we found that the conserved ubiquitin-co...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Yanagitani, Kota, Juszkiewicz, Szymon, Hegde, Ramanujan S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549844/
https://ncbi.nlm.nih.gov/pubmed/28774922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan0178
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