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The ASC-1 Complex Disassembles Collided Ribosomes
Translating ribosomes that slow excessively incur collisions with trailing ribosomes. Persistent collisions are detected by ZNF598, a ubiquitin ligase that ubiquitinates sites on the ribosomal 40S subunit to initiate pathways of mRNA and protein quality control. The collided ribosome complex must be...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7447978/ https://ncbi.nlm.nih.gov/pubmed/32579943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.06.006 |
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