Specificity and effector functions of non-neutralizing gB- specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

Human cytomegalovirus (HCMV) is the most common congenital infection. A gB subunit vaccine (gB/MF59) is the most efficacious clinically tested to date, having achieved 50% protection against primary infection of HCMV-seronegative women. We previously identified that gB/MF59 vaccination primarily eli...

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Publicado no:Virology
Main Authors: Goodwin, Matthew L., Webster, Helen S., Wang, Hsuan-Yuan, Jenks, Jennifer A., Nelson, Cody S., Tu, Joshua J., Mangold, Jesse F., Valencia, Sarah, Pollara, Justin, Edwards, Whitney, McLellan, Jason S., Wrapp, Daniel, Fu, Tong-Ming, Zhang, Ningyan, Freed, Daniel C, Wang, Dai, An, Zhiqiang, Permar, Sallie R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447913/
https://ncbi.nlm.nih.gov/pubmed/32838941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2020.07.009
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