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Radiation causes tissue damage by dysregulating inflammasome–gasdermin D signaling in both host and transplanted cells
Radiotherapy is a commonly used conditioning regimen for bone marrow transplantation (BMT). Cytotoxicity limits the use of this life-saving therapy, but the underlying mechanisms remain poorly defined. Here, we use the syngeneic mouse BMT model to test the hypothesis that lethal radiation damages ti...
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| Publicat a: | PLoS Biol |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7446913/ https://ncbi.nlm.nih.gov/pubmed/32760056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000807 |
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