Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition

PURPOSE: Children with pediatric gliomas harboring a BRAF V600E mutation have poor outcomes with current chemoradiotherapy strategies. Our aim was to study the role of targeted BRAF inhibition in these tumors. PATIENTS AND METHODS: We collected clinical, imaging, molecular, and outcome information f...

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Detaylı Bibliyografya
Yayımlandı:JCO Precis Oncol
Asıl Yazarlar: Nobre, Liana, Zapotocky, Michal, Ramaswamy, Vijay, Ryall, Scott, Bennett, Julie, Alderete, Daniel, Balaguer Guill, Julia, Baroni, Lorena, Bartels, Ute, Bavle, Abhishek, Bornhorst, Miriam, Boue, Daniel R., Canete, Adela, Chintagumpala, Murali, Coven, Scott L., Cruz, Ofelia, Dahiya, Sonika, Dirks, Peter, Dunkel, Ira J., Eisenstat, David, Faure Conter, Cecile, Finch, Elizabeth, Finlay, Jonathan L., Frappaz, Didier, Garre, Maria Luisa, Gauvain, Karen, Bechensteen, Anne Grete, Hansford, Jordan R., Harting, Inga, Hauser, Peter, Hazrati, Lili-Naz, Huang, Annie, Injac, Sarah G., Iurilli, Valentina, Karajannis, Matthias, Kaur, Gurcharanjeet, Kyncl, Martin, Krskova, Lenka, Laperriere, Normand, Larouche, Valerie, Lassaletta, Alvaro, Leary, Sarah, Lin, Frank, Mascelli, Samantha, McKeown, Tara, Milde, Till, Morales La Madrid, Andres, Morana, Giovanni, Morse, Helena, Mushtaq, Naureen, Osorio, Diana S., Packer, Roger, Pavelka, Zdenek, Quiroga-Cantero, Eduardo, Rutka, James, Sabel, Magnus, Salgado, Duarte, Solano, Palma, Sterba, Jaroslav, Su, Jack, Sumerauer, David, Taylor, Michael D., Toledano, Helen, Tsang, Derek S., Valente Fernandes, Mariana, van Landeghem, Frank, van Tilburg, Cornelis M., Wilson, Bev, Witt, Olaf, Zamecnik, Josef, Bouffet, Eric, Hawkins, Cynthia, Tabori, Uri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Clinical Oncology 2020
Konular:
Original Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446502/
https://ncbi.nlm.nih.gov/pubmed/32923898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00298
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