LGG-59. REMARKABLE OBJECTIVE RESPONSE AND FAVORABLE SURVIVAL FOR BRAF-V600E CHILDHOOD LOW-GRADE GLIOMAS TO BRAF INHIBITORS COMPARED CONVENTIONAL CHEMOTHERAPY

Activation of the MAPK pathway represents a hallmark of pediatric low-grade glioma (pLGG) and is frequently caused by BRAF alterations. BRAF-V600E represent an aggressive type of pLGG with less than optimal response to conventional chemo-radiation approaches. While clinical trials using BRAF-V600E i...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Zapotocky, Michal, Ryall, Scott, Fukuoka, Kohei, Stucklin, Ana Guerreiro, Bennett, Julie, Sumerauer, David, Pavelka, Zdenek, Cruz, Ofelia, Solano, Palma, Garre, Maria Luisa, Hauser, Peter, Frappaz, Didier, Hansford, Jordan, Amayiri, Nisreen, Morse, Helena, Sabel, Magnus, Bechensteen, Anne Grete, Su, Jack, Karajannis, Matthias, Finlay, Jonathan, Eisenstat, David, Canete, Adela, Toledano, Helen, Dahiya, Sonika, Leary, Sarah, Nicolaides, Theodore, Finch, Elisabeth, Mueller, Sabine, Levy, Jean Mulcahy, Ellison, David, Lassaletta, Alvaro, Larouche, Valerie, Ramaswamy, Vijay, Dirks, Peter, McKeown, Tara, Bartels, Ute, Bouffet, Eric, Hawkins, Cynthia, Tabori, Uri
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2018
נושאים:
Abstracts
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6011906/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.399
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