PDCT-08. SUPERIOR OUTCOME FOR BRAF V600E PEDIATRIC GLIOMAS TREATED WITH TARGETED BRAF INHIBITION

BACKGROUND: Children with pediatric low grade glioma’s (PLGG) harboring BRAF V600E mutation have poor outcome due to relative resistance to chemo-radiation and higher risk of malignant transformation. However, the role of targeted BRAF inhibition in these tumors is poorly defined. METHODS: We assemb...

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Publié dans:Neuro Oncol
Auteurs principaux: Nobre, Liana, Zapotocky, Michal, Ramaswamy, Vijay, Ryall, Scott, Bennett, Julie, Balaguer Guill, Julia, Baroni, Lorena, Bartels, Ute, Bornhorst, Miriam, Boue`, Daniel, Chintagumpala, Murali, Cruz, Ofelia, Dahiya, Sonika, Dirks, Peter, Dunkel, Ira, Eisenstat, David, Finch, Elizabeth, Finlay, Jonathan, Frappaz, Didier, Luisa Garre, Maria, Gauvain, Karen, Grete Bechensteen, Anne, Hansford, Jordan, Hauser, Peter, Huang, Annie, Karajannis, Matthias, Kaur, Gurcharanjeet, Larouche, Valerie, Lassaletta, Alvaro, Leary, Sarah, Lin, Frank, McKeown, Tara, Milde, Til, Morales La Madrid, Andres, Morse, Helena, Mushtaq, Naureen, Osorio, Diana, Packer, Roger, Pavelka, Zdenek, Salgado, Duarte, Sabel, Magnus, Solano, Palma, Su, Jack, Sumerauer, David, Toledano, Helen, van Tilburg, Cornelis, Wilson, Bev, Bouffet, Eric, Hawkins, Cynthia, Tabori, Uri
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Pediatric Clinical Trials
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847848/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.771
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