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Model-Assisted Designs for Early-Phase Clinical Trials: Simplicity Meets Superiority

Drug development enterprise is struggling because of prohibitively high costs and slow progress. There is urgent need for adoption of novel adaptive designs to improve the efficiency and success of clinical trials. A major barrier is that many conventional designs are inadequate for modern drug deve...

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Опубликовано в: :JCO Precis Oncol
Главные авторы: Yuan, Ying, Lee, J. Jack, Hilsenbeck, Susan G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Clinical Oncology 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446379/
https://ncbi.nlm.nih.gov/pubmed/32923856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.19.00032
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