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Lysosome Positioning Influences mTORC2 and AKT Signaling
Growth factor signaling is initiated at the plasma membrane and propagated through the cytoplasm for eventual relay to intracellular organelles such as lysosomes. The serine/threonine kinase mTOR participates in growth factor signaling as a component of two complexes, mTORC1 and mTORC2. mTORC1 assoc...
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| Опубликовано в: : | Mol Cell |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7446307/ https://ncbi.nlm.nih.gov/pubmed/31130364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.05.009 |
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