Loading...
Lysosomal mTORC2/PHLPP1/Akt regulate chaperone-mediated autophagy
Chaperone-mediated autophagy (CMA), a selective form of degradation of cytosolic proteins in lysosomes, contributes to maintenance of proteostasis and to the cellular adaptation to stress. CMA substrates are delivered by a cytosolic chaperone to the lysosomal surface, where upon unfolding, are inter...
Saved in:
| Published in: | Mol Cell |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506737/ https://ncbi.nlm.nih.gov/pubmed/26118642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.05.030 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|