Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

While vaccine development will hopefully quell the global pandemic of COVID-19 caused by SARS-CoV-2, small molecule drugs that can effectively control SARS-CoV-2 infection are urgently needed. Here, inhibitors of spike (S) mediated cell entry were identified in a high throughput screen of an approve...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Chen, Catherine Z., Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer, Straus, Marco R., Zhu, Wei, Shinn, Paul, Guo, Hui, Shen, Min, Klumpp-Thomas, Carleen, Michael, Samuel G., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444289/
https://ncbi.nlm.nih.gov/pubmed/32839777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.10.197988
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