Quantum Dot‐Conjugated SARS‐CoV‐2 Spike Nanoparticles for SARS‐CoV‐2 infection modeling and drug discovery

The SARS‐CoV‐2 virus binds to host cell surface ACE2 on the plasma membrane via the spike protein's receptor binding domain. Our work has resulted in the generation of a versatile imaging probe using recombinant Spike receptor binding domain conjugated to fluorescent quantum dots (QDs). This pr...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Gorshkov, Kirill, Susumu, Kimihiro, Chen, Jiji, Xu, Miao, Pradhan, Manisha, Zhu, Wei, Hu, Xin, Breger, Joyce, Wolak, Mason, Oh, Eunkeu
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239633/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fasebj.2021.35.S1.00420
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