The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules

[Image: see text] Understanding the SARS-CoV-2 virus’ pathways of infection, virus–host–protein interactions, and mechanisms of virus-induced cytopathic effects will greatly aid in the discovery and design of new therapeutics to treat COVID-19. Chloroquine and hydroxychloroquine, extensively explore...

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Bibliografiset tiedot
Julkaisussa:ACS Infect Dis
Päätekijät: Gorshkov, Kirill, Chen, Catherine Z., Bostwick, Robert, Rasmussen, Lynn, Tran, Bruce Nguyen, Cheng, Yu-Shan, Xu, Miao, Pradhan, Manisha, Henderson, Mark, Zhu, Wei, Oh, Eunkeu, Susumu, Kimihiro, Wolak, Mason, Shamim, Khalida, Huang, Wenwei, Hu, Xin, Shen, Min, Klumpp-Thomas, Carleen, Itkin, Zina, Shinn, Paul, Carlos de la Torre, Juan, Simeonov, Anton, Michael, Sam G., Hall, Matthew D., Lo, Donald C., Zheng, Wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2020
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771250/
https://ncbi.nlm.nih.gov/pubmed/33346633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00349
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