Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis

[Image: see text] The first step of SARS-CoV-2 infection is binding of the spike protein’s receptor binding domain to the host cell’s ACE2 receptor on the plasma membrane. Here, we have generated a versatile imaging probe using recombinant Spike receptor binding domain conjugated to fluorescent quan...

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Publicado en:ACS Nano
Autores principales: Gorshkov, Kirill, Susumu, Kimihiro, Chen, Jiji, Xu, Miao, Pradhan, Manisha, Zhu, Wei, Hu, Xin, Breger, Joyce C., Wolak, Mason, Oh, Eunkeu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2020
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482579/
https://ncbi.nlm.nih.gov/pubmed/32845122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c05975
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