Identifying SARS-CoV-2 Entry Inhibitors through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles

[Image: see text] While vaccine development will hopefully quell the global pandemic of COVID-19 caused by SARS-CoV-2, small molecule drugs that can effectively control SARS-CoV-2 infection are urgently needed. Here, inhibitors of spike (S) mediated cell entry were identified in a high throughput sc...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Chen, Catherine Z., Xu, Miao, Pradhan, Manisha, Gorshkov, Kirill, Petersen, Jennifer D., Straus, Marco R., Zhu, Wei, Shinn, Paul, Guo, Hui, Shen, Min, Klumpp-Thomas, Carleen, Michael, Samuel G., Zimmerberg, Joshua, Zheng, Wei, Whittaker, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586456/
https://ncbi.nlm.nih.gov/pubmed/33330839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00112
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