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Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens
The synthesis of quinolinic acid from tryptophan is a critical step in the de novo biosynthesis of nicotinamide adenine dinucleotide (NAD(+)) in mammals. Herein, the nonheme iron-based 3-hydroxyanthranilate-3,4-dioxygenase responsible for quinolinic acid production was studied by performing time-res...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7443976/ https://ncbi.nlm.nih.gov/pubmed/32732435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005327117 |
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