Crystal structure of 3-hydroxyanthranilic acid 3,4-dioxygenase from Saccharomyces cerevisiae: A special subgroup of the type III extradiol dioxygenases

3-Hydroxyanthranilic acid 3,4-dioxygenase (3HAO) is a non-heme ferrous extradiol dioxygenase in the kynurenine pathway from tryptophan. It catalyzes the conversion of 3-hydroxyanthranilate (HAA) to quinolinic acid (QUIN), an endogenous neurotoxin, via the activation of N-methyl-D-aspartate (NMDA) re...

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Main Authors: Li, Xiaowu, Guo, Min, Fan, Jun, Tang, Wenying, Wang, Deqiang, Ge, Honghua, Rong, Hui, Teng, Maikun, Niu, Liwen, Liu, Qun, Hao, Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242480/
https://ncbi.nlm.nih.gov/pubmed/16522801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051967906
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