A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels

In mammals, temperature-sensitive TRP channels make membrane conductance of cells extremely temperature dependent, allowing the detection of temperature ranging from noxious cold to noxious heat. We progressively deleted the distal carboxyl terminus domain (CTD) of the cold-activated melastatin rece...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Díaz-Franulic, Ignacio, Raddatz, Natalia, Castillo, Karen, González-Nilo, Fernando D., Latorre, Ramon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443914/
https://ncbi.nlm.nih.gov/pubmed/32747539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004303117
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